Dr. Attia's Philosophy on Supplementation Dr. Attia's Philosophy on Supplementation

Inside Dr. Peter Attia’s Drug and Supplement Regimen for Health Optimization

Healthy’s Summary

Dr. Peter Attia takes a highly personalized and science-driven approach to supplementation and medication, focusing on longevity, metabolic health, cognitive function, and disease prevention. His regimen includes carefully selected supplements and prescription medications based on lab markers, lifestyle factors, and genetic predispositions. While Attia tailors his approach to his individual needs, his methodology can serve as a guide for others looking to optimize their health.

Curious about what supplements may work best for you? Start a chat for personalized recommendations!

Dr. Attia’s Philosophy on Supplementation & Medication

Rather than taking a one-size-fits-all approach, Attia follows a data-driven, precision-medicine philosophy. He continuously adjusts his regimen based on blood work, genetic markers, and emerging research. He also prioritizes lifestyle interventions (nutrition, exercise, and sleep) before relying on supplementation.

Key Areas of Focus in His Regimen

1. Longevity & Cellular Health

  • Rapamycin (mTOR Inhibitor) — Taken intermittently to promote autophagy and slow aging.
  • Metformin (or Berberine as an alternative) — Used to enhance insulin sensitivity and possibly extend lifespan.
  • NAD+ Precursors (NR/NMN) — Supports mitochondrial function and cellular repair.

2. Cardiovascular & Metabolic Health

  • Omega-3 Fatty Acids — High-dose EPA/DHA for reducing inflammation and supporting heart health.
  • Apolipoprotein B (ApoB) Lowering Medications — Such as statins or PCSK9 inhibitors, if necessary.
  • Magnesium (RBC Magnesium) — Supports vascular function, muscle health, and sleep.

3. Cognitive Function & Brain Health

  • Magnesium Threonate — May enhance cognitive performance and neuroprotection.
  • Creatine Monohydrate — Supports brain energy metabolism and muscle function.
  • Lion’s Mane Mushroom — A nootropic believed to support nerve growth and cognitive function.

4. Hormonal Optimization

  • Testosterone Replacement Therapy (if clinically indicated) — For maintaining muscle mass, cognitive sharpness, and metabolic health.
  • DHEA — Supports hormonal balance and resilience to stress.

5. Sleep & Recovery

  • Melatonin (Low Dose) — Helps regulate circadian rhythm.
  • Glycine & Magnesium Glycinate — May promote relaxation and deeper sleep.
  • Apigenin — A natural compound that supports sleep onset and stress reduction.

The Takeaway

Dr. Attia’s supplement and medication regimen is highly individualized and evolves based on his health data and latest research. His approach underscores the importance of testing before supplementing, avoiding unnecessary compounds, and prioritizing lifestyle factors first.

Interested in how Dr. Attia’s recommendations apply to your own health and routine? Start a chat now and get personalized insights and recommendations.

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